PRODUCT DEVELOPMENT - COGNITIV
Ever since the pandemic, working from home has become the new normal. While working from home may have its own benefits, it also presents some challenges. The increased number of distractions at home and a lack of focus can decrease our productivity. This issue may be addressed in a number of ways, using different forms of brain-boosting supplements.
An example of such supplements is Nootropics which our proprietary formula, COGNITIV has been specifically designed and tested by Neuroscientists for the work-from-home workforce.
INGREDIENTS, RESEARCH & STUDIES
HOW DOES COGNITIV WORK
COGNITIV is classified as a “Nootropic” which are specialized compounds that are used to boost the individual's cognitive abilities and brain functions. Other than boosting cognitive functions. Nootropics are common supplements used to enhance an individual's mental energy, creativity, and focus. This is why nootropics are also often referred to as brain boosters. (1)
Nootropics, such as COGNITIV are often referred to as brain boosters because of their ability to enhance the availability of certain neurotransmitters in the human brain. These include Serotonin and Dopamine. The increased levels of neurotransmitters in the brain help improve the overall memory and focus of the individual.Other than boosting the levels of neurotransmitters, COGNITIV also works by stimulating the production of new neurons in the brain.The neurons are also referred to as the basic cells of the brain. The increased number of new neurons in the brain makes the brain more capable of learning new things. Improved brain health helps protect the individual from brain damage and the negative effects of stress. In addition, the antioxidant effects of the nootropics further prevent the cellular aging process. (2)
DMAE
DMAE, which is also known as Deanol, is one of the active ingredients of COGNITIV. It is produced naturally in the human body. It may also be attained from external sources, which include fatty fish like Sardines, Salmon, and Anchovies. It is known for its ability to increase brain functions and improve an individual's mood and overall memory.
Experts also recommend DMAE for the management of conditions like Alzheimer's disease, depression, ADHD, and dementia. DMAE work by elevating the levels of Acetylcholine in the body. Acetylcholine is a neurotransmitter that is essential for the brain signaling the body. Acetylcholine is also important for pain responses, muscle contraction, and sleep regulation in the body. Another way through which DMAE may work in the body is by preventing the accumulation of beta-amyloid in the brain. By preventing the buildup of Beta-amyloid, DMAE helps protect the individual from the age-related decline of cognition and loss of memory. Hence, DMAE is effective for the brain, especially in aging individuals.
DMAE's benefits are reported in several studies conducted over the years. One of the major benefits for which DMAE is popularly used is its effects on memory.One such study, which was conducted as a randomized clinical trial in 2009, showed a protective effect of DMAE in test subjects who were induced to have memory deficits. The results of the study showed that those who were given DMAE had a higher level of the neurotransmitter acetylcholine in their brain. These increased levels lead to improvement in spatial memory. The study concluded by stating that individuals may take DMAE for long-term preservation of their memory, as it helps protect the memory against damaging agents and medications like Scopolamine. (3)
DMAE is also found to have an effect on an individual's mood. Studies have shown this agent to be effective in promoting a positive mood and preventing the development of a bad mood. An example of such a study is the one conducted in 1977 on individuals who were experiencing a cognitive decline due to aging. These participants commonly suffered from anxiety, depression, and constant irritability. The results of the study showed that those individuals who took DMAE were found to have a better mood with increased motivation. (4)
However, the benefits of DMAE are not only limited to the memory and mood of individuals; it may also offer dermatological benefits. This is because those who take supplements with DMAE regularly are found to have a reduction in their wrinkles and correction of sagging skin. This was also proven in a study that was reported in the American Journal Of Clinical Dermatology as a randomized clinical trial. The results of the study found DMAE to be effective for the correction of fine lines on the forehead and around the eyes. (5)
Another similar study also found DMAE to improve skin hydration and overall appearance. (6)Bacopa Monnieri
Bacopa is also referred to as Bacopa Monnieri and is derived from a plant that has been used for ayurvedic purposes for many years. Bacopa Monnieri works by increasing the levels of certain chemicals in the brain, which are important for a person's memory, learning, and cognitive processes. This is why it is also often recommended to individuals who are at risk for Alzheimer's disease.
Bacopa is a powerful antioxidant, which allows it to protect against cell damage caused by oxidants and free radicals. Since the damage induced by free radicals become a causative factor for a number of chronic diseases like diabetes, cardiac conditions, and cancer – the antioxidant effects of Bacopa may also protect the individual from these diseases. (7)
The antioxidant effect of Bacopa Monnieri is due to the unique and powerful constituents found in it. The active principle in Bacopa is known as Bacosides, which works by neutralizing free radicals. It also works by preventing these free radicals from reacting with the fat molecules found in the body. The process of reaction of free radicals with the fat molecules is known as lipid peroxidation. This process is responsible for numerous conditions of the body, which include Parkinson's, Alzheimer's, and other neurodegenerative diseases. Hence, intake of Bacopa Monnieri may prevent the development of these diseases. (8)
Other than its antioxidant effects on the body, Bacopa is also known to have a positive impact on memory, especially in aging individuals. Studies have also found Bacopa to be effective in reversing the signs of memory loss. (9)
In addition to its effects on memory, it may also enhance the brain functions of the individual. This was also proven in a number of studies, one of which showed the effects of Bacopa supplements on mice. The results of the study showed that Bacopa was not only effective for improving spatial learning, but it may also enhance memory retention. (10)
The way in which Bacopa is able to enhance memory is by affecting the lengths of neurons and their branches. It increases the length of the dendrites of the neurons and their branching, which helps enhance memory and learning.
Another similar study was conducted on a total of 46 individuals who were in a healthy state. The study period was conducted over a period of 12 weeks, during which they were given 300 mg of Bacopa. The study's results showed that taking Bacopa increased the learning rate and memory and the speed of visual processing. This may increase the productivity of the individual and allow them to be more efficient at work. (11)Tyrosine
Tyrosine is a type of amino acid that plays different roles in the body. It is naturally produced in the body through the conversion of another amino acid known as Phenylalanine.
It is not only responsible for the production of hormones and proteins in the body but also for the chemicals responsible for transmitting brain signals. These include Dopamine and Norepinephrine.
Dopamine and norepinephrine are involved in brain focus and alertness. This is why Tyrosine is commonly used in nootropic supplements that boost cognitive performance and concentration.
Tyrosine can also be attained from external food sources and is found in many high protein food products such as soy products, chicken, turkey, fish, peanuts, almonds, avocados, bananas, milk, cheese, yogurt, cottage cheese, lima beans, pumpkin seeds, and sesame seeds. Hence individuals who are looking to improve memory, performance in stressful environments, and improve performance and balance mood may benefit from higher tyrosine levels in the body.
Tyrosine is one of the most crucial active ingredients included in COGNITIV. There are many benefits of Tyrosine, one of which is its ability to improve mental performance, especially in a work environment and stressful situations. The benefits of Tyrosine against stress are particularly beneficial as stressful situations may not only negatively affect an individual's memory and attention but also their reasoning. It may also reduce the total amount of neurotransmitters found in the body. This has been proven in studies, which show that test participants exposed to stressful situations are more likely to have a decline in the total number of their neurotransmitters. However, when the study participants were given supplements containing Tyrosine, there was a reversal in the reduction of neurotransmitters. This also led to the restoration of memory. (12)
This was also proved in another study conducted on a total of 22 females. The results of the study showed that females who took Tyrosine had a significant improvement in their working memory participants, particularly during mentally challenging tasks. By improving the working memory of the females tested, Tyrosine assisted them to concentrate more and complete tasks. (13)
Another similar study which was conducted on 22 individuals, showed the positive effects of Tyrosine on the Cognitive flexibility of the individual. This allowed the individuals who took Tyrosine to switch between tasks and thoughts. Hence, the quicker an individual can switch between different tasks, the greater their cognitive flexibility. This could be beneficial in stressful situations and times where there is an excessive workload. (14)
In addition to its positive effects on cognition, Tyrosine is also frequently used for sleep disturbances and sleep disorders. Studies show that even a single dose of Tyrosine can be effective at keeping individuals who lost a night's sleep to stay awake and alert for 3 hours longer. (15)
The study concluded by stating that Tyrosine may be used as a means to counteract the reduction in work performance in individuals with sleep loss.
GABA
Gamma-Aminobutyric acid is also commonly referred to as GABA. This is an amino acid that is commonly found in the body. Other than being an important amino acid, it also acts as a neurotransmitter that is naturally found in the human nervous system. GABA works by inhibiting or modulating the activity of other neurotransmitters, which allows more efficient communication between different neurons.
On the other hand, individuals who have lower levels of GABA in their bodies are more likely to suffer from Insomnia and other sleep disturbances, depression, and even anxiety. Additionally, deficiency in GABA causes anxiety, restlessness, and obsessive behavior, symptoms often seen in ADHD, which can be treated by supplementing with approved products that include adequate amounts of GABA. Nootropics that contain GABA are found to increase the levels of other essential neurotransmitters in the body, which allows it to provide both physical and mental benefits. Individuals working from home who are taking GABA supplements may benefit by having increased productivity and concentration at work. Nootropics containing GABA supplements may work for individuals of all ages who are older than 18 years of age. It is used to enhance creativity and well-being and reduce stress levels and manage anxiety.
Some of the most common benefits of supplementing with GABA include the management of anxiety, sleep disturbances, hypertension, and even stress and fatigue.
A number of studies have investigated the benefits of GABA for anxiety. One such study, which was conducted in 2006, showed that individuals who took supplements containing GABA had an improved feeling of relaxation, particularly during stressful situations. The anxiety-relieving effects and relaxation were most commonly reported after one hour of taking the supplements. (16)
Moreover, GABA is also found to be effective for fatigue. One study, which was conducted in 2011, including individuals from Japan, further proved these effects. The study included a total of 30 individuals who were given either 25mg or 50 mg of GABA. The results of the study showed that the individuals who took drinks containing GABA had improvements in both their mental and physical fatigue. (17) When the two drinks were compared, one containing a higher concentration of GABA was found to be more effective than the one with a lower concentration.
This was further proven in a study from 2009, where the study participants were given chocolates containing 28 mg of GABA. The results showed that these individuals experienced a reduction in their stress levels when performing a problem-solving task. (18)
Other than its positive effects on stress, anxiety, and fatigue, it may also be effective for sleep disturbances. This was proven in a study conducted in 2018, which showed that individuals who took 300 mg of GABA 60 minutes before going to bed were able to fall asleep faster as compared to those who did not. Moreover, the individuals also reported improvements in their overall sleep quality after taking GABA for a month. (19)
GABA is also effective for cases of high blood pressure. Stressful work environments can lead to high blood pressure, which not only negatively affects productivity but also may lead to long-term health complications. One study from 2003 showed that individuals who took milk products containing GABA were able to reduce blood pressure in individuals who had been suffering from hypertension for several weeks. (20)





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